For specifically astronomical functions I use MaxDSLR (from www.cyanogen.com) because it is well-established and reliable, follows standard Windows practices, and is organized to make important concepts clear. Thus, when telling you how to process images, I can concentrate on what you're actually accomplishing rather than the quirks of the software. What's more, MaxDSLR doesn't just process images; it can also control the camera, run a webcam autoguider, and capture and process video planet images.
MaxDSLR has a big brother (MaxIm DL, from the same manufacturer) and a head-on competitor (ImagesPlus, from www.mlunsold.com), both of which offer even more features but are more complex to use. They work with astronomical CCD cameras as well as DSLRs and webcams.
As an alternative to MaxDSLR I also use Nebulosity (from www.stark-labs.com). This is a quick and simple image processing package for DSLR users, similar in overall design to MaxDSLR but much lower priced. (The two make a good pair.) Like MaxDSLR, Nebulosity not only processes images, but also controls the camera in the field. It runs on the Macintosh as well as the PC.
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